(2 Apr 2025)
RESTRICTION SUMMARY:
ASSOCIATED PRESS
Chula Vista, California – 1 April 2025
1. Zoom in shot of board that reads Get your shingles vaccine here today.
ASSOCIATED PRESS
Stanford, California – 31 March 2025
2. SOUNDBITE (English) Pascal Geldsetzer, Stanford University:
"Well, so there is an increasing body of evidence that shows that viruses that preferentially target your nervous system and that remain hibernated in your nervous system for life, may be implicated in the development of dementia. And one such virus, of course, is the chickenpox virus."
ASSOCIATED PRESS
Chula Vista, California – 1 April 2025
3. Shot of board that reads shingles can be whaaat? Prevented!
ASSOCIATED PRESS
Stanford, California – 31 March 2025
4. SOUNDBITE (English) Pascal Geldsetzer, Stanford University:
"But there’s also this increasing body of literature of research showing that vaccines have broader immune mechanisms beyond the specific antibody responses that they have been designed to elicit, and that these broader immune mechanisms may have benefits for chronic diseases."
ASSOCIATED PRESS
ARCHIVE: London – 8 October 2018
5. Close of computer monitor showing MRI scan showing deterioration and cell death of 62 year old Alzheimer’s patient over seven years
ASSOCIATED PRESS
Stanford, California – 31 March 2025
6. SOUNDBITE (English) Pascal Geldsetzer, Stanford University:
"Well, we know that inflammation is a key process in many chronic diseases, and it’s also increasingly being recognized as being a key process in the development of dementia. So yeah, so reducing this inflammation through shingles vaccination may have benefits."
ASSOCIATED PRESS
Chula Vista, California – 1 April 2025
7. Close up shot of board that reads Get your shingles vaccine here today.
ASSOCIATED PRESS
Stanford, California – 31 March 2025
8. SOUNDBITE (English) Pascal Geldsetzer, Stanford University:
"Well, we estimate that roughly 1 in 5 new dementia diagnoses over a seven year follow up period are averted through shingles vaccination, which is to us a very exciting finding. It’s a very robust finding."
ASSOCIATED PRESS
ARCHIVE: London – 8 October 2018
9. Close of PET scan of healthy brain (left) and Alzheimer’s patient’s brain (right) red areas show degeneration and cell death
ASSOCIATED PRESS
Stanford, California – 31 March 2025
10. SOUNDBITE (English) Pascal Geldsetzer, Stanford University:
"And It’s most importantly a finding that we keep seeing and data set after data set from different populations and different countries that rolled out shingles vaccination in similar ways using this very specific date of birth eligibility cutoffs."
ASSOCIATED PRESS
Bedford, New Hampshire – 2 September 2011
11. STILL a box of frozen vaccine is seen at the Bedford Pharmacy in Bedford, N.H. New Hampshire
ASSOCIATED PRESS
Stanford, California – 31 March 2025
12. SOUNDBITE (English) Pascal Geldsetzer, Stanford University:
"All our natural experiments, these clean studies that allow us to get at cause and effect in a pretty convincing manner and thing are all focused on the old live attenuated vaccine, because that’s simply the vaccine that happened to be ruled out using these data cutoffs. And so to really give us the best shot of showing that there is a benefit from shingles vaccination, we want to use the vaccine that we have all this evidence for."
ASSOCIATED PRESS
Chula Vista, California – 1 April 2025
13. Shot of Shingrix shingles vaccine box with vials in front
ASSOCIATED PRESS
Stanford, California – 31 March 2025
ASSOCIATED PRESS
ASSOCIATED PRESS
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