New adaptive Parkinson’s technology will increase real time movement for patients

(13 Jan 2025)
NETHERLAND’S PARKINSON’S

SOURCE: ASSOCIATED PRESS

RESTRICTION SUMMARY:

LENGTH: 5.05

ASSOCIATED PRESS
Amsterdam, Netherlands – 13 January 2025

1. Pan from Dr Martijn Beudel to Eric van Breda, Parkinson’s patient
2. Close tilt down of Eric van Breda, Parkinson’s patient
3. SOUNDBITE (English) Eric van Breda, Parkinson’s patient:
“It started with the difficulty in typing on the computer and as my wife is a neurologist we found out that it was Parkinson’s quite rapidly. I went to see and a neurologist and have an MRI and had the diagnosis within two weeks, then my whole life kind of collapsed, not due to the symptoms, but the prospect of a life (with Parkinson’s).”

4. Pan shot from a tablet with software which reads stimulation from the DBS implant and transmitters that are placed on patient’s chest during software update
5. Tracking shots of doctor placing transmitters on Eric van Breda’s chest
6. Mid of tablet connecting with the brain implant
7. Mid of doctors reacting on the sound confirming the success connection
8. SOUNDBITE (English) Dr Martijn Beudel, Neurosurgeon, University Medical Centres, Amsterdam:
“So deep brain stimulation is an established therapy in which the neurosurgeon places leads deep into the brain that are connected via a wire to the pulse generator that’s providing pulses which reduce (result) to dramatic improvements of movement problems in patients with, for example, Parkinson’s disease.”

9. Tilt up of doctors
10. Close tilt up of patient Eric van Breda
11. Close of tablet showing how van Breda’s brain is responding
12 Wide of doctors talking to van Breda
13. SOUNDBITE (English) Dr Martijn Beudel, Neurosurgeon, University Medical Centres, Amsterdam:
“So with this new adaptive form of stimulation, we’re able to adjust the therapy based on the actual needs of the patients. So how do we do this? We now are able to record neural activity from the DBS leads that were previously only able to stimulate. This neural activity tells us something about symptom severity, and that makes us able to control the stimulation based on the needs of the patients.”

14. Close up on tablet showing adapted brain stimulations
15. Wide of patient
16. SOUNDBITE (English) Eric van Breda, Parkinson’s patient
“The Parkinson’s, did progress quite rapidly. I had to take much more, more and more medication to a point where the side effects were so terrible that I couldn’t cope anymore with medication. So there was a point that I was so well, like, stressed out. It stimulates you, but at the same time, it makes you feel stressed. So I had difficulties in sleeping, difficulty coming out of bed. All kinds of unpredictable difficulties.”

17. Tilt from Dr. Martiin Beudel to tablet
18. SOUNDBITE(English) Dr Martijn Beudel, Neurosurgeon at the University Medical Centres, Amsterdam:
“So, we have been investigating these methods in the laboratory in which we see that patients were able to move faster and we’ve also have experienced hands on that patients improve their movements during this adaptive form of stimulation. However, we still wait for larger cohorts of patients to see whether larger groups of patients actually have a benefit of this and we hope to see that in a nearby future.”

18. Zoom into doctors and tablet which is tracking the deep brain stimulation
19. SOUNDBITE (English) Eric van Breda, Parkinson’s patient:
"I didn’t dare to to hope for it anymore. So I now again can make plans and think of the future, so that’s that’s a big gain for me."

20. Close of Beudel talking with patient in background

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