Seattle scientist one of the winners of Nobel Prize in chemistry

(9 Oct 2024)
RESTRICTION SUMMARY:

ASSOCIATED PRESS
Seattle – 9 October 2024
1. Various of David Baker being interviewed at his home
2. SOUNDBITE (English) David Baker, Nobel Prize in Chemistry winner:
"You just get a phone call. And in this case, it was very it was funny because they actually had my son Benjamin’s phone number and they called him first and then he gave them my phone number. So they called me."
3. David Baker and his wife
4. SOUNDBITE (English) David Baker, Nobel Prize in Chemistry winner:
"Well, it was it was really, really exciting. Actually, I couldn’t really think because my wife was screaming so loud, so…"
5. Various of press conference start at University of Washington
6. SOUNDBITE (English) David Baker, Nobel Prize in Chemistry winner:
"I started, about, a little over 20 years ago trying to design new proteins. And, Brian Coleman came to my lab and he actually designed the first brand-new protein. And at that time, we were really, really excited that we could make up new proteins from scratch. And we thought that, we hoped it would be possible to make proteins that had all sorts of new functions. But I don’t think we would have guessed that things have come up, would have come, we’d have come this far as we actually have today in terms of making proteins to solve all kinds of different current day problems."
7. Baker at press conference
8. SOUNDBITE (English) David Baker, Nobel Prize in Chemistry winner:
"We’re designing proteins to break down plastic. We’re designing proteins to break down pollutants. We’re designing as a sort of design proteins that will only that will function like for cancer to function and destroy tissue at the tumor, but nowhere else. So be very selective, much more selectively target the tumor. We’re designing proteins to bind to the to the amyloid forming proteins that cause Alzheimer’s, Alzheimer’s and other neurodegenerative diseases."
9. Baker posing with colleagues
10. SOUNDBITE (English) Ana Mari Cauce, President of the University of Washington:
"If you look at David’s work, this is about taking these great basic science ideas and pushing them out so that they make a difference in the world."
11. Wide of press conference
12. SOUNDBITE (English) David Baker, Nobel Prize in Chemistry winner:
"I think we’re really just at the beginning. We figured out how to design new proteins. We figured out how to make them, you know, bind to cancer targets, for example. And we’re starting and we’re getting better at learning how to make them catalyze chemical reactions. So we’ve really learned a lot about how to design proteins with new functions. So I think now it’s tremendously exciting is to look at the vast array of problems that humans face and try and design proteins that solve these problems."
13. Baker at conference
STORYLINE:
The Nobel Prize in chemistry was awarded Wednesday to three scientists for their breakthrough work predicting and even designing the structure of proteins, the building blocks of life.

The prize was awarded to David Baker, a biochemist at the University of Washington in Seattle, and to Demis Hassabis and John Jumper, who both work at Google DeepMind, a British-American artificial intelligence research laboratory based in London.

Baker designed a new protein in 2003 and his research group has since produced one imaginative protein creation after another, including proteins that can be used as pharmaceuticals, vaccines, nanomaterials and tiny sensors, the Nobel committee said.

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