Israeli ground troops are reported to have advanced into the heart of the southern Gazan city of Rafah.
Journalists and witnesses there say Israeli tanks have seized control of a key roundabout in the centre of the city.
The Israeli military has said it is investigating the possibility that weapons stored in a nearby compound caught fire after an Israeli air strike in Rafah on Sunday, triggering a blaze in a tent camp for displaced Palestinians that killed dozens of people.
Meanwhile, the Hamas-run health ministry has said 21 people were killed and 64 injured in a displaced persons camp in Rafah on Tuesday amid continuing Israeli shelling. Israelās military has denied carrying out a strike on the area.
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